During embryonic development in a mammalian model, a mutation completely knocks out the function of the transcription factor SOX9. However, the embryo’s karyotype is normal (46,XY), and its SRY gene on the Y chromosome is perfectly intact and actively transcribed. What will be the developmental fate of this embryo’s indifferent bipotential gonads?

In a species of tropical fish, crossing a true-breeding midnight blue fish with a true-breeding bright yellow fish yields F1 offspring that are entirely solid neon green. Which of the following best describes the molecular reality occurring in the cells of these neon green F1 heterozygotes?

In an experimental grain crop, seed weight is controlled by two duplicate genes acting additively (9:6:1). Double homozygous dominant plants (AABB) produce heavy seeds, double homozygous recessive plants (aabb) produce ultra-light seeds, and individuals carrying a dominant allele at only one locus (A_bb or aaB_) produce intermediate-weight seeds. If you cross two dihybrid plants (AaBb x AaBb), how many out of 16 expected offspring will display the intermediate seed weight phenotype?

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An Erlang distribution models a random variable as the time elapsed before a fixed number of successes occur; for instance, one might model the time a commuter waits for their subway car as an Erlang distributed random variable. For

Shown in panels A-D are single stranded DNA based oligonucleotides. The key provides information on the modifications that may be present at the 5′ and 3′ ends. Select the oligonucleotide that best fits the description provided below.                               Oligonucleotide that can be used in standard PCR as a primer for amplification Oligonucleotide that can be used in real-time PCR as a primer for amplification Oligonucleotide that can be used as a probe for real-time PCR Oligonucleotide that can be used as a primer in Sanger based DNA sequencing Oligonucleotide that would be adhered to a slide for use in a DNA microarray Oligonucleotide that would be used as a primer in SMRT based DNA sequencing

Define the term ‘epigenetics’. (1pt) Explain with identical twins are a good example of epigenetic regulation. (1pt)

Which of these will increase the coverage of a confidence interval? Select all that apply. 

What information is obtained from a DNA microarray assay?