Determine, for each individual case listed below, whether a…
Determine, for each individual case listed below, whether a certain genetic change will result in high activity of the gene product of a proto-oncogene. Answer Yes or No for each case. Gain of a chromosome that contains the proto-oncogene. A mutation that introduces a stop codon 10 amino acids after the codon for the initiator methionine. A mutation within the coding sequence that makes the protein less active. A change in the promoter of the proto-oncogene, causing the normal protein to be transcribed and translated at an abnormally high level.