Diagram and describe (A) the first three levels in the struc…
Diagram and describe (A) the first three levels in the structure or folding of a single polypeptide chain. Include examples of the structures formed at each level. (3 pts.) (B) Indicate the bonds, interactions, and forces that determine or stabilize each level of structure. (3 pts.) (C) Each of the following reagents or conditions will denature a protein: urea, polar organic solvents, detergent and extreme pH. For one of these reagents, diagram and describe what the reagent/condition does to destroy native protein structure. In this description indicate whether the mechanism of denaturation involves primarily entropy or enthalpy or both. (3 pts.) (D) What type of amino acid functional group is typically found in the interior of a water-soluble globular protein? What type is found on the exterior of a globular protein? (3 pts.) (E) Diagram and describe the experiment providing the evidence that supports the idea that the amino acid sequence of proteins alone is sufficient to determine their final folded structure? (3 pts.)