Huntington disease: H = dominant; h = normal Molecular marke…
Huntington disease: H = dominant; h = normal Molecular marker (MM) alleles: M1 = molecular marker allele 1; M2 = allele 2; M3= allele 3 In 50 families analyzed, one parent is HM2/hM3 (H__M2 h__M3) and the other parent is hM1/hM1 (h__M1 h__M1). In 50 children: -20 have the Huntington allele (H) and molecular markers M1 and M2 -20 have two normal alleles (h) and molecular markers M1 and M3 -5 have the Huntington allele (H) and molecular markers M1 and M3 -5 have two normal alleles (h) and molecular markers M1 and M2 What is the recombination frequency? How many map units apart is the Huntington allele from the molecular marker?