Ms. Rodriguez, a 27-year-old woman, presents to the outpatie…
Ms. Rodriguez, a 27-year-old woman, presents to the outpatient clinic with fatigue, pallor, and frequent nosebleeds. She reports a history of heavy menstrual periods and that her brother and maternal uncle both had “bleeding problems.” On examination, she is pale and has several small bruises on her arms and legs. Her vital signs are stable. Labs: Hemoglobin: 8.5 g/dL (12–16) Hematocrit: 26% (36–46) Platelets: 140,000/μL (150,000–400,000) WBC: 6,800/μL (4,000–11,000) PT: 21 sec (11–15) aPTT: 78 sec (25–40) **Family testing previously revealed her brother had Hemophilia A. Which genetic characteristic applies to Hemophilia A, as seen in Ms. Rodriguez’s family?