People with cystic fibrosis (CF) are homozygous recessive fo…
People with cystic fibrosis (CF) are homozygous recessive for mutations in a gene known as CFTR. These mutations cause the CFTR protein to become dysfunctional, and it is unable to move chloride to the cell surface. Ultimately mucus can build up in organs, and in the lungs, the mucus clogs the airways and traps bacteria, leading to infections, inflammation, and respiratory failure. In a human population, if 9 in 10,000 newborn babies are born with CF, what are the expected frequencies of the dominant (A1) and recessive (A2) alleles according to the Hardy-Weinberg model in that population?