Questions 56-58 refer to the following scenario: You are doi…
Questions 56-58 refer to the following scenario: You are doing an experiment on a new class of G protein–coupled receptor. You make several cell lines that each express the receptor, the corresponding G protein, and adenylyl cyclase. Each cell line has different mutations in these components. You decide to measure cyclic AMP (cAMP) in the cells of each cell line to understand the effect of each of these mutations. For each of the descriptions of the mutations, indicate whether the amount of cAMP in the cells will increase, decrease, or stay the same compared to cells with no mutations in the signaling pathway. A mutation in the a subunit of the G protein prevents it from binding to adenylyl cyclase but not the receptor. The amount of cAMP in cells will: