Step 3 – Evaluate how statins help reduce the concentration…
Step 3 – Evaluate how statins help reduce the concentration of LDL cholesterol in a person’s blood and recommend an appropriate statin dose. Directions: Use Figure 3 to answer questions. The last question has multiple steps. First, calculate the change in the rate at which cholesterol is converted to bile salts needed to achieve this reduction. Next, determine the change in the rate at which liver cells import cholesterol required to produce the calculated change in bile salt conversion. Finally, the relationship between statin dosage and the rate of cholesterol import into liver cells is used to calculate the necessary dosage of the drug. Express your answer as a whole number. For example, if you calculate a probability of 243.54, report a value of 244.