The following is true about distribution of lipophilic drugs…
The following is true about distribution of lipophilic drugs: 1. They do not dissolve in the lipid membranes.2. They move across most biologic membranes.3. Blood flow does not influence its distribution.4. Lipophilic drugs with low molecular weight cannot move into the interstitium.5. Lipophilic drugs with high molecular weight pass through the slit junctions of the capillaries.