The heat-stable toxin of Escherichia coli (STa) binds to int…
The heat-stable toxin of Escherichia coli (STa) binds to intestinal epithelial cells, acting as a full agonist to increase intracellular cGMP thereby stimulating CFTR in crypts and inhibiting coupled NaCl absorption in villi. Based on your knowledge of stimulus-response coupling, which drug from the following list would be the best treatment for STa-induced diarrhea?