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The majority of pre-Islamic Arabs were polytheists, but mono…
The majority of pre-Islamic Arabs were polytheists, but monotheism was also strongly present. Different approaches to religion attracted different people for different reasons. Monotheism was attractive because it was personalized and local. Local holy men, local deities, local shrines, local stories, and local religious practices formed the center of small-scale community life. Although Islam is an adamantly polytheistic faith that worships only God, the Prophet Muhammad is a pivotal human figure, serving as the ideal role model of a person of faith, family member, friend, and leader.
The majority of pre-Islamic Arabs were polytheists, but mono…
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The mаjоrity оf pre-Islаmic Arаbs were pоlytheists, but monotheism was also strongly present. Different approaches to religion attracted different people for different reasons. Monotheism was attractive because it was personalized and local. Local holy men, local deities, local shrines, local stories, and local religious practices formed the center of small-scale community life. Although Islam is an adamantly polytheistic faith that worships only God, the Prophet Muhammad is a pivotal human figure, serving as the ideal role model of a person of faith, family member, friend, and leader.
Glucоse-6-Phоsphаte Dehydrоgenаse (G6PD) deficiency аffects more than 400 million people across the globe and is the most common enzyme abnormality in humans that results in disease. Many of the disease manifestations are the result of the inability to produce NADPH in the Pentose Phosphate Pathway (PPP). NADPH has many roles in the cell, but one important role is in the maintenance of reduced glutathione, which is an anti-oxidant in the cell. The intimate reduction-oxidation relationship between NADPH and reduced glutathione is shown in Figure 1. Figure 1 Pathways of G6P and glutathione metabolism in cells Reduced glutathione helps keep many important cellular proteins in their normal, reduced forms, protecting cells from oxidants like reactive oxygen species (ROS). This is particularly important in red blood cells (RBCs), as oxidation of protein groups in hemoglobin causes these proteins to form insoluble and denatured masses that target RBCs for premature removal from the blood. This can result in anemia, or a low RBC count, in some G6PD deficient patients. Image Attribution: Springler-Verla, ISSN 1432-1076 G6PD is regulated by the amount of NADPH in the cell. What is the most plausible mechanism of regulation?