A 58-year-old patient reports gradual onset of low back pain…
A 58-year-old patient reports gradual onset of low back pain over the past three months. The pain is constant, not relieved by rest, and often wakes the patient at night. The patient also notes a recent unintentional weight loss of 12 pounds and a history of prostate cancer. Which finding most strongly increases the likelihood that the patient’s low back pain is due to a malignant process?