A 64-year-old woman with emphysema (forced expiratory volume…

A 64-year-old woman with emphysema (forced expiratory volume in one second (FEV1) of 1.35) is found to have a 1 cm solitary pulmonary nodule in the peripheral left lower lobe on routine chest x-ray. The only other abnormality on the film is hyperinflated lung fields. Chest computed tomography scan reveals that the lesion abuts the pleura and has no evidence of calcification within it. What is the most appropriate initial management?

The 24-year-old patient is admitted after a drug overdose. S…

The 24-year-old patient is admitted after a drug overdose. She was intubated in the field for unresponsiveness. In the emergency department, her initial blood pressure is 100/70 mm Hg, for pulse is 65 beats/min, and her respiratory rate is 6 bpm. She has pinpoint pupils, diffuse crackles on chest exam, and the toxicology screen positive for cocaine, methadone, and diazepam. Which of the following ventilator settings would be the most appropriate given her clinical presentation?