Enzyme X has a Km for substrate A which is twice as large as…

Enzyme X has a Km for substrate A which is twice as large as its Km for substrate B.  If the enzyme is added to a solution containing equal, but low concentrations of A and B, and Vmax for A and B are equal: (Remember – the lower the Km, the higher the affinity)

We discussed several case studies of mutation disorders. Thi…

We discussed several case studies of mutation disorders. This is a very rare disorder caused by a point mutation that activates a deletion of nearly 50 amino acids of the lamin A protein found in the nuclear membrane. The syndrome affects children by causing an 8-10x accelerated rate of aging. The average lifespan is only about 13 years with an overall effect of cachexia, hair loss, osteoporosis, cardiovascular disease, and other aging-related conditions.