(6 pts) Name three key technical advances that enabled routine high-resolution cryo-EM structure determination. For each, briefly describe how it improved data quality or resolution.

(4 pts) Protein crystals are ordered arrays of protein molecules in three dimensions. Space group describes the symmetry of the crystal lattice. Explain the reason why only 65 space groups are possible for protein crystals, in comparison to a total of 230 observed for inorganic or organic small molecules. 

(3 pts) What does the B-factor measure? 

79Ft with chronic cancer-related pain is receiving fentanyl 50 mcg IV every 2 hours PRN for severe pain. Due to a change in clinical status, the provider decides to switch to IV hydromorphone. Using equianalgesic dosing, what is the most correct dose of hydromorphone? IV fentanyl 100 mcg ≈ IV morphine 10 mg  

A patient has been taking the monoamine oxidase inhibitor (MAOI) phenelzine (Nardil) for 6 months. The patient wants to go to a party and asks the RN, “Will just one beer be a problem?” Which advice from the nurse is correct?

The domain of a relation R is the set of real numbers. x is related to y under relation R if |x+y|≥2. Select the description that accurately describes relation R.

BONUS 2pts Find .

Graph G is defined by the arrow diagram below. Select all the properties that accurately describe the following sequence with respect to graph G: ⟨3,1,4,2,3⟩

Download the Exam2.ipynb file and the following three files into a new folder on your computer. sales_2026.csv input.txt marine_observations.csv Start a new Jupyter notebook session from that folder.  Complete the three programming problems contained in the notebook file, save your work and upload the completed notebook file to this question. You may use Jupyter Notebooks and Python on your local computer to complete this portion of the test.   Problem 1 – 7 points. Problem 2 – 7 points. Problem 3 – 7 points.

This style of art has its emphasis on popular consumer culture, mechanical processes, image appropriation, and the merging of high and low culture: