Loss-of-function mutations in PLCzeta (Phospholipase C zeta)…
Loss-of-function mutations in PLCzeta (Phospholipase C zeta) are associated with human infertility. Explain why this is the case, making sure to include three things: 1) the function of PLCzeta, 2) the main biological consequence of PLC zeta loss-of-function human fertilization, and 3) whether the mutation is likely to be found in the male or female partner in a case of infertility.