Nebulin is 3D actin-binding protein that can be found in ske…
Nebulin is 3D actin-binding protein that can be found in skeletal muscles. Nebulin is large in size and functions to stabilize actin and regulate muscle contractions. The gene that codes for nebulin, NEB, is on chromosome 2 in humans. Mutations to the NEB gene can result in mutations in the amino acid sequence of the resulting nebulin protein. If the mutation in the gene causes an amino acid deletion in the sequence of amino acids that make up nebulin, how will this affect the structure of nebulin?