Sulfa drugs are antibiotics that interfere with folic acid s…
Sulfa drugs are antibiotics that interfere with folic acid synthesis by acting as a competitive inhibitor on one of the key enzymes, thereby preventing bacteria from making needed folic acid. By contrast, humans acquire folate through the diet and are therefore not affected by sulfa drugs, with the exception of about 3% of people who have an allergic reaction. As a competitive inhibitor, sulfa drugs bind to ______.